Carboxylic acids and derivatives
eMolecules AstaTech / 3-(4-CARBOXYPHENYL)-PROPIONALDEHYDE ETHYL ESTER / 1g / 112529843 / 67843 / 90.000 / 151864-81-2 / MFCD01631196 / 206.241 / C12H14O3
AstaTech / 3-(4-CARBOXYPHENYL)-PROPIONALDEHYDE ETHYL ESTER / 1g / 112529843 / 67843 / 90.000 / 151864-81-2 / MFCD01631196 / 206.241 / C12H14O3
Medchemexpress LLC L-Aspartic acid, N-(phosphonoacetyl)-, trisodium salt | 70962-66-2 | 98.0% | 321.06 | 10 MG
Sparfosic acid trisodium is a DNA antimetabolite agent and a potent inhibitor of aspartate transcarbamoyl transferase, which catalyzes the second step of de novo pyrimidine biosynthesis. It synergistically enhances the cytotoxicity of a combination of 5-fluorouracil (5-FU) and interferon-alpha (IFN) against human colon cancer cell lines. It is for research use only and not sold to patients.
- DNA antimetabolite agent
- Potent inhibitor of aspartate transcarbamoyl transferase
- Synergistically enhances the cytotoxicity of 5-FU and IFN against human colon cancer cell lines
- Treatment with 490 mg/kg in mice bearing B16 melanoma increased life-span by 77% to 86%
- Lewis lung carcinoma is highly sensitive, with treatment leading to a cure in 50% of mice
Apexbio Technology LLC NB-598 Maleate 155294-62-5 5mg
NB-598 Maleate is a small-molecule inhibitor targeting squalene epoxidase (SE) an essential enzyme in cholesterol biosynthesis It is designed to inhibit SE thereby disrupting the oxygenation of squalene and affecting downstream synthesis of cholesterol intermediates particularly within farnesol-dependent pathways leading to triglyceride biosynthesis NB-598 Maleate exerts its biological activity primarily through inhibition of squalene epoxidase In mouse pancreatic islet models NB-598 Maleate reduces insulin secretion under both basal and glucose-stimulated conditions Additionally this compound inhibits calcium voltage-dependent (CaV) ion channels in cellular assays Based on these pharmacological properties NB-598 Maleate holds research potential in studying cholesterol biosynthesis pathways lipid metabolism insulin regulation and the physiological role of CaV channels
Apexbio Technology LLC Moxalactam (sodium salt) 64953-12-4 500mg
Moxalactam sodium salt (CAS 64953-12-4) is a small-molecule -lactam antibiotic belonging to the oxacephem subclass It is designed to inhibit bacterial cell wall biosynthesis by targeting penicillin-binding proteins (PBPs) Moxalactam sodium salt exerts its biological activity by interfering with PBPs thereby preventing cell wall synthesis In in vitro studies Moxalactam sodium salt demonstrates broad-spectrum inhibition of various Gram-positive Gram-negative and anaerobic bacteria including Klebsiella pneumoniae Escherichia coli Haemophilus influenzae and Neisseria gonorrhoeae Typical MIC values for susceptible organisms are generally in the low microgram-per-milliliter range Based on these pharmacological properties Moxalactam sodium salt holds research potential in antibacterial susceptibility assays studies on antibiotic resistance mechanisms and investigations of bacterial cell-wall synthesis pathways
eMolecules 180182-07-4 | Ambeed | tert-Butyl 2-(piperidin-4-yl)acetate | 100mg | 570579168 | A613961 | MFCD06738957 | 199.294 | C11H21NO2
Benzoxazole | Ambeed | 273-53-0 | MFCD00005765 | 119.123 | C7H5NO | 98.000 | c1nc2ccccc2o1 | 25g | 525136227
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Sigma Aldrich Fine Chemicals Biosciences Propyl formate >=97% | 110-74-7 | MFCD00003295 |
Propyl formate >=97% | Purity: >=97% | Mol Wt: 88.11 | 110-74-7 | MFCD00003295 |
Medchemexpress LLC ORIC-101 | 2222344-98-9 | 98.92% | 501.74 | 1 ML
ORIC-101 | 2222344-98-9 | 98.92% | 501.74 | 1 ML